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Research Specialist, Assay Development & Screening

Weill Cornell Medical College

New York, NY
Weill Cornell Medical College
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Job Details

Position Summary

Independently develops and performs primary and secondary screening assays to identify therapeutic antibody candidates at the Tri\-Institutional Therapeutics Discovery Institute \(Tri\-I TDI\)\.

Job Responsibilities

+ Performs primary binding and cell\-based assays with antibodies using a variety of readout technologies\.

+ Performs development activities relating to the optimization and validation of immunoassays including developing assay specific controls

+ Assists in screening project initiation including transfer of assays from principal investigators laboratory to TDI\.

+ Evaluates, recommends, and develops new techniques to assist in overall laboratory efficiency\.

+ Ensures laboratory quality assurance goals and standards are met\. Evaluates results of quality control trends and implements corrective action when needed\.

+ Writes/amends laboratory operating protocols and implements new technology and protocols as needed\.

+ May independently or semi\-independently, designs and carries out experiments\. Analyzes and interprets experimental results and provides input related to subsequent experimental designs\.

+ Responsible for tissue & cell culture activities\.

+ Prepares and maintains detailed records, logs and summary reports of all procedures and results including graphs, scientific calculations, and statistical analysis charting\.

+ Conducts library research and literature searches using various computer systems\. Assists in editing scientific publications, abstracts and posters\.

+ Conducts library research and literature searches using various computer systems\. Assists in editing scientific publications, abstracts and/or posters\.

+ Maintains inventory of supplies, equipment and/or reagents\. May order supplies/equipment/reagents as authorized or ensure that needs are escalated appropriately\. Receives supply orders and confirms accuracy of delivery\. May assist with cost control\.

+ Audits and screen vendors/suppliers to evaluate the quality of products and equipment they supply\. Corresponds with them for technical support pertaining to those products\.

+ Ensures a clean working area and is responsible for washing and storing glassware\.

+ Ensures the safe laboratory practices are followed, including the use and disposal of chemicals and hazardous materials\.

+ May need to assist in the orientation and training of new investigators, fellows, residents, and technical staff and/or provide working supervision to lower level laboratory staff\.

+ May be responsible for animal husbandry, genotyping, surgeries, post\-operative care, behavioral testing, sectioning and histology\.

+ May perform routine molecular biology laboratory procedures, such as PCR, protein and DNA electrophoresis, cloning and DNA preparation\.

+ May run routine biochemistry assays including western blotting and RT\-PCR\.

+ May perform microscopic imaging analyses\.

+ May be responsible for the receipt, storage, cataloguing and shipment of samples within and between institutions\.


+ Bachelor's Degree


Bachelor's degree in biochemistry, molecular biology or related field\.

A minimum of 3\-5 years of experience in antibody screening and assay development in the pharmaceutical or biotechnology industry or in an academic lab\.

In\-depth experience in plate based assays

Extensive knowledge in all aspects of liquid handlers including programing, operation and maintenance is highly desirable

Experience in flow cytometry assays and/or surface plasmon resonance \(SPR\) a plus

Knowledge, Skills and Abilities

+ Strong interpersonal skills and ability to communicate technical information, both written and orally, in a readily understood manner, with colleagues and collaborators at all levels

+ Critical independent thinking, prioritization of tasks, strong problem\-solving, and excellent communication and presentation skills

+ Timely delivery of team goals and ability to build productive relationships with colleagues, collaboration partners, and stakeholders

Licenses and Certifications

Working Conditions/Physical Demands

Ability to work flexible hours\.

Weill Cornell Medicine is a comprehensive academic medical center that's committed to excellence in patient care, scientific discovery, and the education of future physicians in New York City and around the world\. Our doctors and scientists\-faculty from Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences, and the Weill Cornell Physician Organization\-are engaged in world\-class clinical care and cutting\-edge research that connect patients to the latest treatment innovations and prevention strategies\. Located in the heart of the Upper East Side's scientific corridor, Weill Cornell Medicine's powerful network of collaborators extends to its parent university Cornell University; to Qatar, where an international campus offers a U\.S\. medical degree; and to programs in Tanzania, Haiti, Brazil, Austria and Turkey\. Our medical practices serve communities throughout New York City, and our faculty provide comprehensive care at NewYork\-Presbyterian Hospital/Weill Cornell Medical Center, NewYork\-Presbyterian/Lower Manhattan Hospital, and NewYork\-Presbyterian/Queens\. At Weill Cornell Medicine, we work together to treat each individual, not just their conditions or illnesses, as we strive to deliver the finest possible care for our patients \- the center of everything we do\. Weill Cornell Medicine is an Equal Employment Opportunity/Minorities/Females/Vet/Disabled employer\.
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